Journal Articles
XIFAXAN®
(rifaximin) 550 mg tablets
Overt HE
2024
Rifaximin plus lactulose versus lactulose alone for reducing the risk of HE recurrence
Sanyal AJ, et al. Hepatol Comm. 2024
Serum ammonia levels do not correlate with overt hepatic encephalopathy severity in hospitalized patients with cirrhosis
Bajaj JS, et al. Clin Gastroenterol Hepatol. 2024
2023
Evaluation of a protocol for rifaximin discontinuation in critically ill patients with liver disease receiving broad-spectrum antibiotic therapy
Ward JA, et al. World J Hepatol. 2023
Real-world evidence of long-term survival and healthcare resource use in patients with hepatic encephalopathy receiving rifaximin-α treatment: a retrospective observational extension study with long-term follow-up (IMPRESS II)
Aspinall RJ, et al. Frontline Gastroenterol. 2023
Predicting hepatic encephalopathy in patients with cirrhosis: a UK population-based study and validation of risk scores
Jones BI, et al. Hepatol Commun. 2023
Integration of cirrhosis best practices into electronic medical record documentation associated with reduction in 30-day mortality following hospitalization
Sherman Z, et al. J Clin Gastroenterol. 2023
Impact of rifaximin use following an initial overt hepatic encephalopathy hospitalization on rehospitalization and costs
Jesudian AB, et al. J Med Econ. 2023
High rifaximin out-of-pocket costs are associated with decreased treatment retention among patients with hepatic encephalopathy
Aby ES, et al. Hepatol Commun. 2023
Role of oral health, frailty, and minimal hepatic encephalopathy in the risk of hospitalization: a prospective multi-center cohort of outpatients with cirrhosis
Bajaj JS, et al. Clin Gastroenterol Hepatol. 2023
Global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis: a prospective cohort study for the CLEARED Consortium
Bajaj JS, et al. Lancet Gastroenterol Hepatol. 2023
Rifaximin use, adherence and persistence in patients with hepatic encephalopathy: a real-world study in the south of Italy
Pandico F, et al. J Clin Med. 2023
Add-on therapeutic effects of rifaximin on treatment-resistant hepatic encephalopathy
Hayakawa Y, et al. Intern Med. 2023
Lack of access to rifaximin upon hospital discharge is frequent and results in increased hospitalizations for hepatic encephalopathy
Stoll AM, et al. Ann Pharmacother. 2023
2022
Hepatic encephalopathy-related hospitalizations in cirrhosis: transition of care and closing the revolving door
Frenette CT, et al. Digestive Diseases and Sciences. 2022.
Hydrogen-producing small intestinal bacterial overgrowth is associated with hepatic encephalopathy and liver function
Yokoyama K, et al. PLoS One. 2022.
2021
Quality of life as a therapeutic objective in the management of hepatic encephalopathy and the potential role of rifaximin-α
Deltenre P, et al. European Journal of Gastroenterology & Hepatology. 2021.
Overt hepatic encephalopathy: current pharmacologic treatments and improving clinical outcomes
Rahimi RS, et al. The American Journal of Medicine. 2021.
Budget impact of optimizing rifaximin-α use for the prevention of recurrent hepatic encephalopathy in The Netherlands
de Jong LA, et al. Journal of Medical Economics. 2021.
Hospitalizations and healthcare costs associated with rifaximin versus lactulose treatment among commercially insured patients with hepatic encephalopathy in the United States
Volk ML, et al. Journal of Medical Economics. 2021.
2020
The role of the hospitalist in the continuum of care for patients with hepatic encephalopathy: treatment of inpatient episodes and preventing outpatient recurrence and readmissions
Flamm SL, et al. Journal of Hospital Management and Health Policy. 2020.
Cost-effectiveness of rifaximin treatment in patients with hepatic encephalopathy
Jesudian AB, et al. Journal of Managed Care & Specialty Pharmacy. 2020.
A retrospective study of drug utilization and hospital readmissions among Medicare patients with hepatic encephalopathy
Vadhariya A, et al. Medicine. 2020.
Hepatic encephalopathy: more than just a change in mental status
Williams JM, et al. Emergency Physicians Monthly. 2020.
2019
Long-term management of hepatic encephalopathy with lactulose and/or rifaximin: a review of the evidence
Hudson M, et al. European Journal of Gastroenterology & Hepatology. 2019.
Understanding the impact of neurologic complications in patients with cirrhosis
Allampati SK, et al. SAGE Open Medicine. 2019.
2018
Evaluation of the cost-effectiveness of rifaximin-α for the management of patients with hepatic encephalopathy in the United Kingdom
Berni E, et al. Current Medical Research and Opinion. 2018.
Complications of cirrhosis in primary care: recognition and management of hepatic encephalopathy
Flamm SL. The American Journal of the Medical Sciences. 2018.
Systematic review of the economic burden of overt hepatic encephalopathy and pharmacoeconomic impact of rifaximin
Neff G, et al. PharmacoEconomics. 2018.
A primary care guide to the diagnosis and management of overt hepatic encephalopathy
Hameed B. Consultant. 2018.
2017
The impact of rifaximin-α on the hospital resource use associated with the management of patients with hepatic encephalopathy: a retrospective observational study (IMPRESS)
Hudson M, et al. Frontline Gastroenterology. 2017.
Diagnosis of cirrhosis and evaluation of hepatic encephalopathy: common errors and their significance for the PCP
Flamm SL. The Journal of Family Practice. 2017.
2016
Cost-effectiveness analysis of rifaximin-α administration for the reduction of episodes of overt hepatic encephalopathy in recurrence compared with standard treatment in France
Kabeshova A, et al. Therapeutic Advances in Gastroenterology. 2016.
Natural history of patients taking rifaximin-α for recurrent hepatic encephalopathy and risk of future overt episodes and mortality: a post-hoc analysis of clinical trials data
Bannister CA, et al. Clinical Therapeutics. 2016.
How to diagnose and manage hepatic encephalopathy: a consensus statement on roles and responsibilities beyond the liver specialist
Shawcross DL, et al. European Journal of Gastroenterology & Hepatology. 2016.
Review article: potential mechanisms of action of rifaximin in the management of hepatic encephalopathy and other complications of cirrhosis
Bajaj JS. Alimentary Pharmacology & Therapeutics [Supplement]. 2016.
The burden of rehospitalization for patients with liver cirrhosis
Desai AP, et al. Hospital Practice. 2016.
2015
Understanding the complexities of cirrhosis
Muir AJ. Clinical Therapeutics. 2015.
Overt hepatic encephalopathy in Italy: clinical outcomes and healthcare costs
Roggeri DP, et al. Hepatic Medicine. 2015.
Presentation and complications associated with cirrhosis of the liver
Poordad FF. Current Medical Research and Opinion. 2015.
Evaluation of the impact of rehospitalization in the management of hepatic encephalopathy
Saab S. International Journal of General Medicine. 2015.
Prolonged remission from hepatic encephalopathy with rifaximin: results of a placebo crossover analysis
Bajaj JS, et al. Alimentary Pharmacology & Therapeutics. 2015.
2014
Efficacy and tolerability of rifaximin in combination with lactulose in end-stage liver disease patients with MELD greater than 20: a single center experience
Mantry PS, et al. Transplantation Proceedings. 2014.
Reply to: Rifaximin is largely safe and well-tolerated but caution is necessary when taken with statins
Mullen KD. Clinical Gastroenterology and Hepatology. 2014.
Rifaximin is safe and well tolerated for long-term maintenance of remission from overt hepatic encephalopathy
Mullen KD, et al. Clinical Gastroenterology and Hepatology. 2014.
Utility values for specific hepatic encephalopathy health states elicited from the general public in the United Kingdom
Guest JF, et al. Health and Quality of Life Outcomes. 2014.
2013
Impact of pretransplant hepatic encephalopathy on liver posttransplantation outcomes
Teperman LW. International Journal of Hepatology. 2013.
Update on management of patients with overt hepatic encephalopathy
Chacko KR, et al. Hospital Practice. 2013.
Modulation of the fecal bile acid profile by gut microbiota in cirrhosis
Kakiyama G, et al. Journal of Hepatology. 2013.
2012
The intestinal microbiota and liver disease
Bajaj JS, et al. The American Journal of Gastroenterology [Supplement]. 2012.
2011
Lactulose: how many ways can one drug be prescribed?
Lukens B, et al. The American Journal of Gastroenterology. 2011.
Treatment of patients with hepatic encephalopathy: review of the latest data from EASL 2011
Bass N. Journal of Gastroenterology and Hepatology [Supplement]. 2011.
Rifaximin improves driving simulator performance in a randomized trial of patients with minimal hepatic encephalopathy
Bajaj JS, et al. Gastroenterology. 2011.
2010
Rifaximin for the treatment of hepatic encephalopathy
Mantry PS, et al. Transplantation Proceedings. 2010.
Rifaximin for the treatment of hepatic encephalopathy
Mullen K, Prakash R. Expert Review of Gastroenterology & Hepatology. 2010.
The treatment of patients with hepatic encephalopathy: review of the latest data from EASL 2010
Mullen KD. Journal of Gastroenterology and Hepatology. 2010.
Factors affecting compliance and persistence with treatment for hepatic encephalopathy
Neff G. Pharmacotherapy [Supplement]. 2010.
Pharmacoeconomics of hepatic encephalopathy
Neff G. Pharmacotherapy [Supplement]. 2010.
Clinical management of hepatic encephalopathy
Schiano TD. Pharmacotherapy [Supplement]. 2010.
Treatment options for hepatic encephalopathy
Schiano TD. Pharmacotherapy [Supplement]. 2010.
Introduction
Thompson JR. Pharmacotherapy [Supplement]. 2010.
Treatment guidelines for hepatic encephalopathy
Thompson JR. Pharmacotherapy [Supplement]. 2010.
The treatment of hepatic encephalopathy in the cirrhotic patient
Sanyal AJ, et al. Journal of Gastroenterology and Hepatology. 2010.
Rifaximin treatment in hepatic encephalopathy
Bass NM, et al. The New England Journal of Medicine. 2010.
2007
Review article: The current pharmacological therapies for hepatic encephalopathy
Bass NM. Alimentary Pharmacology & Therapeutics. 2007.
Review of the final report of the 1998 Working Party on definition, nomenclature and diagnosis of hepatic encephalopathy
Mullen KD. Alimentary Pharmacology & Therapeutics. 2007.
Review article: The burden of hepatic encephalopathy
Poordad FF. Alimentary Pharmacology & Therapeutics. 2007.
Introduction: The burden, pathophysiology and management of hepatic encephalopathy
Williams R. Alimentary Pharmacology & Therapeutics. 2007.
Review article: Bacterial flora and pathogenesis in hepatic encephalopathy
Williams R. Alimentary Pharmacology & Therapeutics. 2007.