Safe management of adverse effects associated with prescription opioids in the palliative care population: a narrative review 

Zimmerman A, et al. J Clin Med. 2024

Management of constipation in hospitalized patients

Sayuk GS, et al. J Clin Med. 2023

Reductions in all-cause mortality associated with the use of methylnaltrexone for opioid-induced bowel disorders: a pooled analysis

Webster LR, et al. Pain Med. 2023

Efficacy and safety of peripherally acting μ-opioid receptor antagonist (PAMORAs) for the management of patients with opioid-induced constipation: a systematic review 

Rekatsina M, et al. Cureus. 2021.

Management of opioid-induced and non-opioid-related constipation in patients with cancer: systematic review and meta-analysis 

Ginex PK, et al. Oncology Nursing Forum. 2020.

Efficacy and safety of peripherally acting mu-opioid receptor antagonists for the treatment of opioid-induced constipation: a Bayesian network meta-analysis 

Ouyang R, et al. Pain Medicine. 2020.

Systematic review with meta-analysis: efficacy and safety of treatments for opioid-induced constipation 

Vijayvargiya P, et al. Alimentary Pharmacology and Therapeutics. 2020.

Identifying and treating opioid side effects: the development of methylnaltrexone 

Moss J. Anesthesiology. 2019.

Pharmacological treatment of opioid-induced constipation is effective but choice of endpoints affects the therapeutic gain

Nusrat S, et al. Digestive Diseases and Sciences. 2019.

Efficacy of treatments for opioid-induced constipation: systematic review and meta-analysis 

Nee J, et al. Clinical Gastroenterology and Hepatology. 2018.

Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care 

Candy B, et al. Cochrane Database of Systematic Reviews. 2018.

Drugs for treating opioid-induced constipation: a mixed treatment comparison network meta-analysis of randomized controlled clinical trials 

Sridharan K, et al. Journal of Pain and Symptom Management. 2018.

Randomized, double-blind trial of oral methylnaltrexone for the treatment of opioid-induced constipation in patients with chronic noncancer pain

Rauck R, et al. Pain Practice. 2017.

Protocol for a randomised control trial of methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients (MOTION) 

Patel PB, et al. BMJ Open. 2016.

Efficacy of methylnaltrexone for the treatment of opioid-induced constipation: a meta-analysis and systematic review 

Mehta N, et al. Postgraduate Medicine. 2016.

Advances in pharmacotherapy for opioid-induced constipation - a systematic review 

Siemens W, et al. Expert Opinion on Pharmacotherapy. 2015.

Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and meta-analysis

Ford AC, et al. The American Journal of Gastroenterology. 2013.

Efficacy and safety of mu-opioid antagonists in the treatment of opioid-induced bowel dysfunction: systematic review and meta-analysis of randomized controlled trials

McNicol ED, et al. Pain Medicine. 2008.

Mu-opioid antagonists for opioid-induced bowel dysfunction

McNicol ED, et al. Cochrane Database of Systematic Reviews. 2008.

Peripherally acting opioid antagonists in the treatment of opiate-related constipation: a systematic review 

Becker G, et al. Journal of Pain and Symptom Management. 2007.

Oral methylnaltrexone for opioid-induced constipation 

Yuan CS, et al. Journal of the American Medical Association. 2000.